Research Projects
Subject 1. Liquid biopsy to identify epigenetic biomarkers and characterize resistant mechanism from patient blood plasma/serum
- Developing cfRNA-Seq platform using molecular biology and Bioinformatics
- Identifying prognostic markers of circulating tumor nucleic acids in cancer
- Characterization of drug resistant mechanism in lung cancer and prostate cancer
- Identification of biomarkers in neural aggregate diseases
- Developing Bioinformatics pipeline applicable to disease-specification
Subject 2. Preclinical Cancer Biology
- Characterization of drug tolerant state in lung cancer
- Characterization of a novel oncogenic lipophagy regulator
- Studies on personalized radiation therapy
- Studies on the ERAD-regulating factors in response to ER stress
Subject 3. Non-coding RNAs & Cancer
- Characterization of drug tolerant state in TRAIL-induced chemoresistance
- The global meta-analysis of miRNA-target genes in stress responsive pathway
- Characterization of lncRNAs in personalized radiation resistance
Subject 4. Application of Microbiome signatures
- Identifying novel microbiota using Meta-genomic and Meta-Transcriptomic analyses
- Functional characterization of microbiome in disease