The Molecular Dermatology Laboratory (MDL) is a laboratory that systematically studies the structure and physiology of the skin at the molecular level. The skin is the largest organ that regulates the human body through various physiological phenomena as well as a physical barrier that protects the human body from the external environment. Our laboratory explores the mechanisms of occurrence of various skin abnormalities (skin cancer, skin autoimmune diseases, aging, skin inflammation diseases, pigmentation abnormalities, etc.) caused by external stimuli, and develops materials that can improve skin abnormalities. In addition, we are investigating the correlation between the skin's circadian rhythm and its physiology and are conducting research to elucidate the skin function of olfactory receptors ectopically expressed in the skin. Ultimately, through the above-mentioned studies, we aim to find ways to improve and maintain skin homeostasis.

Educational Background

• 1). 2005.3- 2010.2: Department of Manufacturing Pharmacy, College of Pharmacy, Seoul National University (Ph.D.), Major Field: Molecular and cellular biology

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• 2). 1994.3 – 1996.2: Department of Biological Science, Graduate School, KAIST(Korea Advanced Science and Technology) (M.S.), Major Field: Signal transduction

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• 3). 1989.3 – 1993.2: Department of Genetic Engineering, Sung Kyun Kwan university(B.S.)

Experiences

• 1). 2022.03 – present:

  Sungkyunkwan University (Dept. of Integrative Biotechnology)

  Status: Professor

  2). 2015.09 – 2022.02:

  Sungkyunkwan University (Dept. of Integrative Biotechnology)

  Status: Associate Professor

  3). 2012.03 – 2015. 08:

  Eulji University (Dept. of Dermatological Health Management)

  Status: Assistant Professor

  4). 2015. 01 – present:

  Journal of Ginseng Research (ISSN 1226-8453)

  Status: Associate editor

  5). 2021. 01 – present:

  Applied Sciences (ISSN 2076-3417)

  Status: Editorial board member

  6). 2002.03 – 2012. 02:

  Biospectrum Life Science Institute,

  Status: Executive and Research Director

  7). 1995.12 - 2001.5:

  Mogam Biotechnology Research Institute

  Therapeutic Agent Center, Laboratory of Signal Transduction

  Status: Senior Research Scientist

   

Achievement

• 1) Spermidine-induced recovery of human dermal structure and barrier function by skin microbiome. Commun Biol. 2021 Feb 19;4 (1):231. doi: 10.1038/s42003-020-01619-4.

2) The Role of Autophagy in Skin Fibroblasts, Keratinocytes, Melanocytes, and Epidermal Stem Cells. J Invest Dermatol. 2020 Sep;140(9): 1691-1697.

3) Blue Light Irradiation Induces Human Keratinocyte Cell Damage via Transient Receptor Potential Vanilloid 1 (TRPV1) Regulation. Oxid Med Cell Long ev. 2020 Dec 15;2020:8871745. doi: 10.1155/2020/8871745. eCollection 2020.

4) Interleukin4Rα (IL4Rα) and IL13Rα1 are associated with the Progress of Renal Cell Carcinoma through Janus Kinase 2 (JAK2)/Forkhead Box O 3 (FOXO3) Pathways. Cancers (Basel). 2019 Sep 18;11 (9):1394. doi: 10.3390/cancers11091394 

• 5) Globular adiponectin acts as a melanogenic signal in human epidermal melanocytes. Br J Dermatol. 2018 Sep;179 (3):689-701.