1. Molecular Diagnostic

Fast and accurate virus diagnosis methods are crucial, especially in light of COVID-19. PCR is the traditional gold

standard method, but it is time-consuming, expensive, and requires high-skilled labor. To address this, we are

developing a rapid and precise isothermal amplification method for viruses using nanomaterials' plasmonic and

photothermic effects. Additionally, our group aims to create plasmonic, electrical, and photoelectric sensor platforms

using nanomaterials for quick and accurate diagnosis of various diseases. Our goal is to provide a platform for virus

diagnosis with mobile phones anytime, anywhere.

2. Mitochondrial Detection

We are investigating modified hypericin for detecting mitochondria, which are essential organelles responsible for energy

production, cell signaling, and apoptosis. Dysfunctional mitochondria are linked to various diseases, making it crucial to

enhance mitochondrial function. Natural compounds like plant pigments have shown potential in improving mitochondrial

function, and we are exploring a pigment's ability to boost ATP production. We also investigate light as a tool to regulate

the activity of this natural pigment. Our ongoing research has promising results and could contribute to the development

of new therapeutic options for various health conditions.

3. Exosome Detection

In our lab, we are currently working on developing a method for mass production and detection of exosomes.

Exosomes are small extracellular vesicles that play an important role in intercellular communication and are potential

biomarkers for various diseases. However, the current methods for exosome production and detection are often

time-consuming and inefficient. Our goal is to develop a streamlined protocol for exosome isolation and purification that

can be scaled up for mass production. This ongoing work has the potential to facilitate exosome-based diagnostic and

therapeutic applications in the future.

4. Alzheimer's and Brain Lesion-related Diseases

 Alzheimer's disease is a progressive neurodegenerative disease that leads to loss of cognitive ability and ultimately

death. Because there are no treatments, limited treatments mostly focus on symptom management. Amyloid beta

peptide aggregation is a pathological feature of many neurodegenerative diseases. We use nanomaterials to regulate

the aggregation and toxicity of Alzheimer's amyloid beta peptides using excited electrons produced by applying light or

ultrasound stimulation. Considering that the medical use of light and ultrasound is considered an attractive treatment

strategy due to its temporal and spatial controllability and reduced side effects, we provide potential and alternative

treatment solutions for treating Alzheimer's and other brain lesion-related diseases using light.

· Our group uses excited electrons from wave and light to modulate beta amyloid peptide aggregation that cause dementia and brain disease.

· Our group believes that it can provide potential alternatives and solutions to brain disease such as dementia and Parkinson's disease.

5. 2D Semiconducting Graphyne

Our research group is primarily interested in the chemistry of 2D materials and is concentrating on the following areas

• Developing new methods for producing holey graphyne (GY) and graphdiyne (GDY) through bottom-up synthesis

  techniques like in-solution, on-surface, and CVD methods.

• Analyzing and understanding the characteristics of these materials, as well as investigating their potential

  applications in various fields, such as OFET, photodetector, gas sensor, artificial synaptic device, and Alzheimer's

  disease prevention.